Treatment with Interleukin-1 Receptor Antagonist Protein (IRAP) utilizes progressive gene therapy to combat osteoarthritis in your horse. Interleukin-1 (IL-1) is a type of cytokine and is secreted by many types of cells. A cytokine is a chemical secreted by the cells of the immune system to attack infections and apoptotic (damaged or dying) cells. IL-1 is an important part of the inflammatory response but in the case of your horse's joints, sometimes can be detrimental. The joint fluid carries a protein called interleukin-1, which plays an important role in inflammation and accelerates the deterioration of tissues like joint cartilage. Interleukin-1 Receptor Antagonist Protein (IRAP) blocks IL-1 from binding to tissues and inhibits the damaging consequences of IL-1.
The procedure begins with drawing blood from the horse into a syringe. The syringe is specially prepared with glass beads that stimulate production of the antagonist protein and an anticoagulant. The blood is harvested, incubated and centrifuged to separate the plasma (abundant with IRAP) from the blood. Typically, IRAP treatments are administered for three treatments and the horse can usually return to normal work.
"The beauty of A-cell therapy is its simplicity; you merely reconstitute the product from a little bottle and put it in the horse's leg." said Dr. Mitchell. A-Cell is a powerful powder that stimulates healing when injected into an injured tendon or ligament. A horse’s body wants to naturally heal itself, just like any human’s would - A-Cell is a bit of a ‘jump start’ for that very process.
This is a great healing process to increase the horse’s natural healing potential. Plasma is harvested from the horse’s bloodstream, and processed to increase their concentration. Once the solution is concentrated, it can help to heal tendon and ligament injuries, due to its growing properties.
Gone are the days of ‘scary’ shockwave therapy, and all the negative stereotypes that go with it. Shockwave therapy on horses is widely recognized as being able to stimulate healing for various orthopedic injuries. Extracorporeal shockwaves are high-pressure, low frequency sound waves, generated by a device and applied to the affected tissue in a site-specific manner. Shockwaves have been used to treat a range of orthopedic conditions in both humans and animals. When the shockwaves meet tissue interfaces of different densities, the energy contained in the shockwaves is released and interacts with the tissue. The shockwaves appear to relieve pain and accelerate healing within the injured tissue.
Originating in France, mesotherapy was introduced to veterinary practitioners in the United States by Dr. Jean Marie Denoix in 2002. Since its introductions, i thas most commonly been used on horses with chronic back pain and degenerative arthritis of the back and cervical vertebrae. However, mesotherapy is effective in treating a multitude of conditions because it helps reverse the physiology of these conditions and stops the recurrent pain associated with these chronic conditions.
Tildren has the ability to slow the degenerative process in certain bone injuries. It is a newer drug, and we are actively involved in a current study to determine its effectiveness. If it continues to prove its positive attributes, Tildren could be an incredible resource to the community - horses, and people alike!